Pipleline
Developing Products
That Are Potent, Enabling,
Novel and Safe
Oncolytic Virus (rHSV) Pineline

Product

Indication

Drug
Discovery

Pre-clinical

IND

Phase I

Phase II

Phase III

BLA

Commer
cialization

MVR-T3011 IT

MVR-T3011 IT

MVR-T3011 IT

MVR-T3011 IT

MVR-T3011 IV

MVR-T3011 IV

MVR-T3011 IP

MVR-C5252

MVR-C5252

MVR-T7 series
CD19/BCMA/Trop-2/HER2

HNSCC

HNC,Sarcoma

HNSCC

Melanoma

Most Solids

Most Solids

ME2, Bladder3, Ovary

GBM

GBM

Most Solids

US Phase IIa
China Phase IIa
China Phase Ib/IIa
China Phase lla
US Phase I
China Phase l
China 1T+IND Submitted
US Phase l
China IND Approved

Various Administration
Methods
Intravenous


Breakthrough viral vector modification strategy allowing various administration methods to meet broader clinical scenarios

Intratumoral

Breakthrough viral vector modification strategy allowing various administration methods to meet broader clinical scenarios

Intraperitoneal,
intrapleural,
intravesical

Breakthrough viral vector modification strategy allowing various administration methods to meet broader clinical scenarios

Biomarker

Biomarker kit to assess the efficacy of OV products and pre-screen potential patients for oHSV clinical treatment

Platform

Product

R&D/Pilot test/Manufacturing

Drug Quality Control

Clinical Trials

Registration

Approval

Biomarker Program

Biomarker Kit